Convenient, once-daily oral dosing with Oxbryta1*

The recommended dosage of Oxbryta for adults and pediatric patients 12 years and older is 1,500 mg orally once daily

Once-daily icon.

Once daily

If a dose is missed or entire dose is not taken, resume dosing the following day

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3 pills
(1,500 mg)

Without the need for titration

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With or without food

Patients should swallow Oxbryta tablets whole. Do not cut, crush, or chew the tablets

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With or without
hydroxyurea

No laboratory monitoring of Oxbryta required

*Please see Full Prescribing Information and Patient Prescribing Information for complete information on Dosage and Administration.

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Recommended dosage for adults and pediatric patients 12 years and older with hepatic impairment

  • The recommended dosage of Oxbryta in adults and pediatric patients 12 years and older with severe hepatic impairment (Child-Pugh C) is 1,000 mg orally once daily
  • No dosage adjustment of Oxbryta is required for patients with mild or moderate hepatic impairment

Recommended dosage of Oxbryta for adults and pediatric patients 12 years and older when used with concomitant strong or moderate CYP3A4 inducers

  • Avoid concomitant use of strong or moderate CYP3A4 inducers with Oxbryta
  • If concomitant use of strong CYP3A4 inducers is unavoidable, the recommended dosage of Oxbryta is 2,500 mg orally once daily. If concomitant use of moderate CYP3A4 inducers is unavoidable, the recommended dosage of Oxbryta is 2,000 mg orally once daily

Dosing recommendations for Oxbryta in pediatric patients ages 4 to <12 years is based on patient's ability to swallow tablets and patient weight

Once-daily Icon

Once daily

If a dose is missed or entire dose is not taken, resume dosing the following day

Plate and Silverware Icon

With or without food

Do not swallow whole, cut, crush, or chew the tablets for oral suspension. Please see administration instructions below

Tablets Icon

With or without
hydroxyurea

No laboratory monitoring of Oxbryta required

*Please see Full Prescribing Information and Instructions for Use for complete information on Dosage and Administration.

*Please see Full Prescribing Information and Instructions for Use for complete information on Dosage and Administration.

*Please see Full Prescribing Information and Instructions for Use for complete information on Dosage and Administration.

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